Download Aplastic Anemia: Pathophysiology and Treatment by Hubert Schrezenmeier, Andrea Bacigalupo PDF

By Hubert Schrezenmeier, Andrea Bacigalupo

This e-book takes account of the latest findings in laboratory learn and scientific trials to supply a complete and up to date reference at the pathophysiology, epidemiology, analysis and remedy of received and inherited aplastic anemia. in addition to supplying a close evaluate of the pathophysiology of the sickness, the overseas workforce of authors covers all features of administration, together with the confirmed methods of bone marrow transplantation and immunosuppressive therapy, new ways comparable to using hematopoietic development elements and escalated immunosuppression, and debatable matters comparable to stem mobilephone transplantation. additionally incorporated is a crucial overseas consensus rfile on therapy, and a last part concentrates at the inherited syndrome Fanconi's anemia. unique therapy guidance are given, making this the definitive source for hematologists and different clinicians all for the administration and supportive care of sufferers with aplastic anemia. Scientists attracted to bone marrow failure also will locate this a useful reference.

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Holmberg, L. , Leisenring, W. et al. (1994) Aplastic anaemia: analysis of stromal cell function in long term marrow cultures. Blood, 84, 3685–90. , Maeda, H. et al. (1985) Functional changes in marrow stromal cells in aplastic anaemia. Acta Haematologica, 74, 65–9. , Griffiths, S. , Ford, A. M. et al. (1992) Activation of the beta-globulin focus control region precedes commitment to the erythroid lineage. Proceedings of the National Academy of Sciences of the USA, 89, 10618. Keller, G. and Snodgrass, R.

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Brizzi, M. , Avanzi, G. , Gabutti, V. and Bacigalupo, A. (1992) Effect of stem cell factor on colony growth from acquired and constitutional (Fanconi) aplastic anemia. Blood, 80, 382–9. Bartley, T. , Li, Y. , Chang, M. , Nichol, J. L. and Swift, S. (1994) Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell, 77, 1117–24. Camitta, B. , Storb, R. and Thomas, E. D. (1982) Aplastic anemia: pathogenesis, diagnosis, treatment and prognosis.

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